Copaiba essential oil is obtained by steam distillation of the resin collected from Copaifera officinalis, a tree native to Central and South America. It has been described as having a spicy, woody aroma. The primary chemical constituent of Copaiba essential oil is caryophyllene, a bicyclic sesquiterpene that is also found in While caryophyllene is responsible for some of the bioactive properties of Copaiba, many other properties of the oil are attributed to diterpenes uniquely found in Copaiba.